Abstract The molecular mechanisms underlying circuit re-wiring in the mature brain remains ill-defined. An eloquent example of adult circuit remodelling is the hippocampal mossy fiber (MF) sprouting found in diseases such as temporal lobe epilepsy. The molecular determinants underlying this retrograde re-wiring remain unclear. https://www.ngetikin.com/mega-save-NHL-Calgary-Flames-Home-Jersey-iPhone-XR-Skin-p120897-hot-value/